What Is the Recommended AREDS 2 Dosage Supplements?

Staring at your screen, have you ever wondered what more you could do for your eyes? 

As nutritional supplements become integral to our well-being, understanding their dosages is crucial for efficacy and safety. Against a backdrop of rising screen time and aging populations, the potency of AREDS 2 in maintaining eye health cannot be overstated. Let this article be the lens through which you discern the key ingredients for ocular resilience and the nuances of their dosages. 

Recommended Dosage for AREDS 2 Supplements

Understanding the recommended dosage for AREDS 2 supplements is crucial for individuals aiming to manage or slow the progression of age-related macular degeneration (AMD). Following the comprehensive Age-related Eye Disease Study 2 (AREDS 2), healthcare providers often suggest a daily intake of these specially formulated supplements to help maintain macular health.

The AREDS 2 supplement regimen involves taking two doses per day for optimal benefits. These key nutrients have been carefully selected to support eye health and include 500 mg of vitamin C, 400 IU of vitamin E, 2 mg of copper (as cupric oxide), and 80 mg of zinc (as zinc oxide). Additionally, the formula provides 10 mg of lutein and 2 mg of zeaxanthin.

For instance, the Clearsight Eye Vitamin AREDS 2 formula recommends one veggie capsule taken twice a day. Clearsight Eye AREDS 2 Vitamins also provides 20 mg of lutein and 4 mg of zeaxanthin through the patented technology Lutemax 2020. 

The variation in zinc dosage in different products may range from 25 to 80 mg, reflecting conclusions drawn from clinical trials regarding safety and efficacy. Users should always consult with nutrition experts or their health care providers before starting any new supplement, especially if they are at risk for or have a diagnosis of advanced age-related macular degeneration.

The Role of AREDS 2 Supplements in Eye Health

AREDS 2 supplements are a beacon of hope for those grappling with age-related macular degeneration (AMD), a leading cause of vision loss. These supplements are packed with key nutrients, specifically formulated based on extensive research to bolster macular health. The potent combo of vitamin C, vitamin E, copper, zinc, lutein, and zeaxanthin aims to decelerate the course of AMD. Nutrition experts recommend a diligent intake of two doses daily—one in the morning and another in the evening—to achieve optimal eye health benefits.

Transitioning from the original AREDS formula, AREDS 2 swaps out beta carotene for lutein and zeaxanthin, aligning with clinical trials that highlight the connection between beta carotene and an increased risk of lung cancer in smokers. By doing so, AREDS 2 offers a safer pathway to preserve central vision, especially for those at heightened cancer risk.

Complementing a nutrient-dense diet with AREDS 2 supplements serves as a powerful strategy to slow down the progression of AMD. Embracing this regimen, under the guidance of health care providers, is a stride toward maintaining visual acuity and overall eye health in the face of advancing years.

NutrientAREDS 2 Dosage (per day)Clearsight AREDS Dosage (per day)
Vitamin C500 mg300 mg
Vitamin E400 IU400 IU
Zinc80 mg as zinc oxide8.8 mg as zinc citrate (Better Absorption)
Copper2 mg as cupric oxide0.66 mg as copper bisglycinate (Better Absorption)
Lutein10 mg20 mg
Zeaxanthin2 mg4 mg

Key Nutrients for Eye Health

Maintaining a diet rich in specific nutrients is fundamental to eye health, especially to those looking to stave off age-related macular degeneration (AMD). Dark leafy greens such as kale, spinach, and collard greens are not just a low-calorie addition to meals; they’re powerhouses packed with essential vitamins C and E, and carotenoids like lutein and zeaxanthin that are key to maintaining eye health. The saying “eating carrots for good vision” isn’t just an old wives’ tale – the beta-carotene found in carrots is indeed beneficial for the eyes.

The Importance of Vitamins and Minerals

The retina, the layer of tissue at the back of the inner eye, plays a crucial role in vision. Vitamins and minerals have been identified as vital components in maintaining the integrity and function of this sensitive structure. The AREDS 2 formula, laden with antioxidants such as Lutein and Zeaxanthin, vitamins C & E, and essential minerals like zinc and copper, is a scientifically based intervention to mitigate the risk of developing age-related macular degeneration (AMD).

Antioxidants have a unique role; they shield the tissues in our eyes from oxidative damage which can contribute to AMD and cataracts. 

An integrative approach combining a diet rich in colorful fruits and vegetables, similar to the Mediterranean diet, with the targeted supplementation provided by AREDS 2 has been demonstrated to delay the progression of AMD. The high-dose vitamins and minerals encapsulated in the AREDS 2 formulation have been shown to offer a protective effect for individuals with existing AMD or drusen, reducing the risk of macular degeneration development by a significant 25 percent.

Zinc and Its Benefits for Eye Health

Zinc’s role in eye health is multifaceted. It supports the transport of vitamin A across the body to the retina, which is essential for vision. Zinc is intricately involved in creating melanin, the pigment that guards the eyes from harmful UV light. This trace mineral is concentrated in the retina and the vascular layer beneath it, known as the choroid. The Age-Related Eye Disease Study (AREDS) substantiated the use of zinc as a means to impede progress in AMD when included in nonprescription supplements.

The American diet, although varied, often lacks adequate levels of zinc, and low intake has been linked to the advancement of chronic eye conditions. The necessity of this mineral is why the inclusion of zinc oxide is specified in the AREDS 2 dosage recommendations. However, it is important to balance zinc supplementation carefully, as excess may lead to a copper deficiency, underscoring the importance of following the AREDS 2 prescribed dosage for maintaining eye health.

Vitamin E and Its Role in Eye Health

Vitamin E, comprising eight antioxidants known as tocopherols, has a vital protective function for the fatty acid-rich cell membranes in the retina. This antioxidant is instrumental in combating free radicals that can damage cells and lead to degenerative eye conditions. The standard recommended dietary allowance (RDA) for vitamin E is 15 milligrams per day for adults, but the AREDS 2 study found that a higher intake of 400 IU/day was safe and beneficial for those at risk for, or with existing AMD, without adverse effects.

Sources of vitamin E are readily available in foods such as nuts, sunflower seeds, and almonds, which can easily be incorporated into a healthy diet. While these foods provide a natural source of vitamin E, supplementation per AREDS 2 recommendations can ensure sufficient levels for those who need additional support for their eye health.

Vitamin C and Its Role in Eye Health

Vitamin C, known for its antioxidant properties, is critical in maintaining eye health and potentially decreasing the risk of age-related eye diseases. The recommended daily allowance suggests 75 milligrams for women and 90 milligrams for men, however, many ocular health specialists advocate for higher intakes when it comes to eye health, as substantiated by the 500 mg daily dosage outlined in the AREDS 2 formula.

This water-soluble vitamin, found abundantly in fruits and vegetables, notably red peppers, is best consumed in its raw form to avoid degradation through cooking. With its ability to promote healthy ocular blood vessels and possibly lowering cataract risk, vitamin C is an invaluable nutrient for preserving eye health.

Other Essential Vitamins and Minerals for Eye Health

Eye health can benefit from a variety of other foods naturally rich in critical nutrients. Eggs, a good source of zinc, also aid in the absorption of lutein and zeaxanthin, which are fundamental for retinal health. Summer squash boasts a composition rich in lutein, zeaxanthin, zinc, and vitamin C, making it an excellent choice for nurturing eye health.

The value of antioxidants in potentially impeding the progression of AMD cannot be overstated, and winter squash, rich in vitamin A and omega-3 fatty acids, is yet another ally in the quest to maintain optimum eyesight. Recognizing the interplay between nutrients and a healthy diet positions individuals to make informed choices for their ocular well-being.


Following the Age-related Eye Disease Study 2 (AREDS 2) guidelines, individuals are recommended to take two doses of the supplement daily—one in the morning and one in the evening—for optimal effectiveness. These supplements have been specially formulated with lutein and zeaxanthin.

It is important to consult health care providers for personalized advice, considering the ongoing innovation and clinical trials in ocular nutrition. As our understanding of genetic factors in eye health evolves, recommendations may be further tailored to an individual’s needs.

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