AREDS 2 Vitamins & Supplements: Proven Formula for AMD

Understanding AREDS 2 Formula: Essential Vitamins & Supplements for Vision

The AREDS 2 formula represents a significant advance in the ongoing research dedicated to preserving eye health and combating Age-Related Macular Degeneration (AMD), which remains a leading cause of vision loss. The formulation is a specialized blend of vitamins, minerals, and supplements, meticulously designed based on extensive research to provide targeted nutritional support for the eyes. The inclusion of lutein and zeaxanthin in the AREDS 2 formula has been shown to contribute positively to the management of AMD, particularly when these carotenoids substitute beta-carotene, enhancing the safety profile for smokers and non-smokers alike.

One cannot overlook the importance of the right administration of these supplements for optimal eye health. The original AREDS (Age-Related Eye Disease Study) research highlighted the benefits of antioxidants and zinc for those at high risk of advanced AMD. However, the subsequent AREDS 2 study refined this approach, demonstrating that a formula without beta-carotene and added lutein and zeaxanthin, along with omega-3 fatty acids, provided a more efficacious alternative for AMD prevention. Moreover, empirical evidence suggests that these specific vitamins and minerals could potentially slow down the progression of AMD, making them a vital part of the vision care products spectrum.

Food sources rich in the nutrients found in the AREDS 2 formula are undoubtedly beneficial for maintaining general health; however, obtaining the precise levels of these nutrients solely from food can be challenging. Therefore, the development of dietary supplements to bridge this gap has become critical. Clearsight, understanding the pivotal role of such formulations, ensures that its products meet the exacting standards set by the AREDS 2 research, delivering a precise blend of these vital nutrients to support eye health.

  • Lutein: An antioxidant that helps protect and maintain healthy cells in the eyes. Lutein is one of the major pigments in the macular region of the eye and may help improve or maintain macular health and vision acuity.
  • Zeaxanthin: Closely related to lutein, zeaxanthin also supports eye health by filtering harmful high-energy blue wavelengths of light and acting as an antioxidant that protects eye cells from damage.
  • Vitamin C (Ascorbic Acid): An essential vitamin with antioxidant properties that helps to support the immune system and also aids in the regeneration of other antioxidants within the body. For eyes, it contributes to healthy blood vessels and may reduce the risk of cataract formation.
  • Vitamin E (Tocopherol): A powerful antioxidant that protects cells from the damage caused by free radicals. It is believed to play a role in reducing the progression of age-related macular degeneration (AMD) and cataract formation.
  • Zinc (as Zinc Oxide): An essential mineral that plays a vital role in bringing vitamin A from the liver to the retina in order to produce melanin, a protective pigment in the eyes. Zinc is an important component in the maintenance of eye health and may help protect against AMD and night blindness.
  • Copper (as Cupric Oxide): Copper is included in the AREDS 2 formula primarily to prevent copper deficiency anemia, a potential side effect of taking high amounts of zinc. Copper also plays a role in maintaining healthy connective tissues in the eye. 

Addressing conditions such as glaucoma, alongside AMD, with a regimented intake of vision supplements, can fortify the overall health of the eyes. This is why the prudent selection of vitamins and minerals specific to vision, such as those found in the AREDS 2 formula, becomes indispensable. Furthermore, vitamins like C and E and minerals like zinc and copper continue to be fundamental components of these formulations, enhancing the protective qualities of the lutein and zeaxanthin included.

Despite the best efforts in dietary management, the administration of these AREDS 2 supplements is often needed for those at risk or suffering from eye diseases. The drug-like precision with which AREDS 2 vitamins target the specific needs of the macular region advocates for their inclusion in comprehensive eye care, as recommended by eye care experts. 

AREDS 2 Vitamins & Supplements Proven Formula for AMD
  • Supports eye health in individuals with age-related macular degeneration (AMD).
  • Formulated based on extensive research by the National Eye Institute.
  • Contains a precise combination of antioxidants, including vitamins C and E.
  • Features essential minerals such as zinc and copper.
  • Includes lutein and zeaxanthin, which are critical for optimal vision health.
  • May help to reduce the risk of progression to advanced AMD.
  • Designed to improve visual acuity and overall vision quality.
  • AREDS 2 removes beta-carotene, making it safer for smokers and former smokers.
  • Offered in easy-to-take capsules or softgels for convenience.
  • Suitable for vegetarians (depending on the specific product formulation).

AREDS 2 Formulation: Evaluating Risks and Side-Effects for People

The Age-Related Eye Disease Study (AREDS) was a significant milestone in understanding the impact of vitamins and minerals on the progression of age-related macular degeneration (AMD). The AREDS trial, sponsored by the National Eye Institute (NIH), led to the development of AREDS supplements as a recommended treatment approach for certain individuals grappling with this chronic eye disease. The modified gel AREDS formula addressed some of the safety concerns present in the original AREDS formula by substituting beta-carotene with lutein and Zeaxanthin in response to findings linking beta-carotene to increased risk of lung cancer in smokers.

Despite the benefits, it’s crucial for people to consider potential side effects and consult with a doctor before starting any new supplement regimen. The updated AREDS formula, often found in products by Bausch + Lomb under the brand name PreserVision, is tailored to support eye health, particularly for those at high risk of progressing from intermediate to advanced AMD. However, preserving vision through nutritional means isn’t without its considerations. Even the gel AREDS delivery system, designed for ease of use, might not be suitable for everyone depending on their individual health circumstances.

For instance, discussions with a doctor are vital to ascertain the appropriate dosage and to ensure the patient isn’t allergic or sensitive to specific components within the AREDS supplements. People should be aware of possible digestive discomfort or allergic reactions, even if these occurrences are rare. In addition to macular degeneration, advanced AMD patients need to remain mindful of their overall health, as certain conditions may intersect with the nutrients provided in these supplements. Cancer patients especially require a discussion with their healthcare providers regarding suitable products, considering the modification of beta carotene in the AREDS formula due to associated cancer risks.

Furthermore, the delivery of AREDS-related information to the public and the manner in which it’s interpreted can play a crucial role in a patient’s health choices. With extensive information available about the AREDS and AREDS2 formulations, people should seek credible advice and sift through the information for a clear understanding of what these formulas entail. A doctor’s insights can make a difference in how individuals with a disease like AMD manage their condition via supplement intake. For those considering a new product, reliable sources such as the NIH can provide the code of guidance needed to traverse the plethora of choices and product claims.

AREDS supplements have exhibited effectiveness in slowing the progression of age-related macular degeneration, yet it’s imperative that people receive comprehensive information and personalized advice before incorporating them into their health regimen. The intricate balance of potential risks versus eye health benefits underscores the importance of medical oversight. For those exploring the use of AREDS formula supplements, an informed conversation with a doctor is not just recommended, it’s a critical step in safeguarding one’s ocular and overall well-being.

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Risks and Side Effects

  • Mild upset stomach
  • Slight headache
  • Dry mouth sensation
  • Metallic taste in the mouth
  • Temporary indigestion or bloating
  • Low-grade diarrhea or constipation
  • Lightheadedness
  • Minor skin rash or itching

How AREDS 2 Products Can Help Preserve Vision Health

The pursuit of maintaining eye health in the face of age-related macular degeneration (AMD) has led to a significant advancement: the formulation of AREDS 2 vitamins and supplements. This tailored blend of nutrients is specifically designed to address the macular degeneration that threatens the vision of millions. People grappling with this disease have found hope in these scientifically-backed products, particularly as food alone may not provide adequate levels of the necessary vitamins to thwart the progression of AMD.

Consuming AREDS 2 supplements is akin to providing a defensive shield for the eyes, which are susceptible to the deleterious effects of macular degeneration. A meticulous combination of vitamin C, vitamin E, zinc, copper, lutein, and zeaxanthin—all integral components of the AREDS 2 formula—has been recommended following the National Eye Institute’s (NEI) Age-Related Eye Disease Studies (AREDS). The gel forms of AREDS 2, or gels AREDS, have also made it easier for people to incorporate these nutrients into their daily regimen.

Focused on eye care, Clearsight meticulously incorporates these elements into our products, understanding that each vitamin plays a pivotal role in safeguarding vision health. The lutein and zeaxanthin in our supplements specifically target the macular region of the eye. As our customers’ health is paramount, we ensure that our multi-vitamin products contain the NEI-recommended amounts of these critical nutrients, a commitment that is especially important for those at an elevated risk of advanced AMD.

Several trials have put the AREDS 2 formula under scrutiny, with the most comprehensive being the AREDS 2 clinical trial. Data from these studies have influenced eye care professionals to advocate the continued usage of macular degeneration supplements, highlighting their ability to slow disease progression. Epidemic levels of vision impairment due to AMD have thus prompted a surge in the recommended intake of such eye health supplements.

Engaging with Clearsight, a brand dedicated to exemplary eye care, ensures that customers receive products based on the scientifically endorsed AREDS 2 formula. Our multivitamins have been optimized to deliver therapeutic dosages that mirror successful trials, such as the AREDS 2 study, which specifically examined 2 mg of zeaxanthin and Lutein alongside 80 mg of zinc. Furthermore, our products provide actionable care for maintaining eye health, a mission aligned with the rigorous standards of the NEI.

All said prevention and early intervention are key in the fight against macular degeneration, making sustained contact with eye care providers essential. Being informed about the benefits of our specially formulated products, including contact details for further guidance, empowers individuals to take charge of their vision health. The comprehensive nature of our Clearsight products, featuring the acclaimed AREDS 2 formula, reinforces our commitment not only to providing sustenance for the eyes but also to fortifying overall food intake with these critical supplements. Therefore, while Bausch + Lomb initiated the original AREDS research, it is through rigorous ongoing developments that we at Clearsight endeavor to offer the most advanced and beneficial products for our customers’ eye health.

Benefits and Features of AREDS 2 Vitamins & Supplements

  • Slows the progression of age-related macular degeneration (AMD) in individuals with intermediate to advanced stages.
  • May reduce the risk of developing advanced AMD, particularly among high-risk individuals such as those with large drusenoid deposits.
  • Improves dietary intake of nutrients crucial for ocular health, such as lutein and zeaxanthin, which are not always adequately consumed in a regular diet.
  • Enhances retinal pigment density by providing lutein and zeaxanthin, which are both important for filtering harmful blue light.
  • Supplies antioxidants, like vitamin C and vitamin E, which combat oxidative stress and may protect the eyes from damage caused by free radicals.
  • Provides zinc and copper, which are essential minerals that aid in the maintenance of healthy retinal function and vision support.
  • Helps maintain the structure and integrity of the macula, the central part of the retina responsible for detailed central vision.
  • Supports overall eye health and may enhance visual acuity in individuals with AMD by supplying key nutrients that the eyes need.
  • May enhance contrast sensitivity, thereby improving the ability to discern objects against a background, which is often a challenge for those with AMD.
  • Potentially contributes to a better quality of life by maintaining vision for longer periods in individuals at risk for progression of AMD.


  1. National Eye Institute: Provides comprehensive details on AREDS 2 supplements for Age-Related Macular Degeneration, including uses, risks, side effects, and ingredients. It’s a pivotal resource for understanding how these supplements can slow down vision loss in people with intermediate AMD. Visit the National Eye Institute
  2. National Eye Institute (FAQs): Offers answers to frequently asked questions about omega-3s, the function of copper in AREDS/AREDS2 supplements, the concentration of zinc, and risks associated with high doses of certain vitamins in the AREDS formulations. Read the FAQs at the National Eye Institute
  3. National Institutes of Health (NIH): A report on a study confirming the benefits of supplements for slowing age-related macular degeneration. This source includes findings from 10 years of AREDS2 data, discussing the increased efficacy of the AREDS2 formula compared to the original and the benefit of eliminating beta-carotene. Visit the National Institutes of Health

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